Diagnostic accuracy of double density sign on CT scan of para-nasal sinuses for fungal sinusitis taking microbiology culture as gold standard

Authors

  • Hadia Wali Department of ENT, Head and Neck Surgery, Shifa International Hospital, Islamabad, Pakistan.
  • Shayan Shahid Ansari Department of ENT, Head and Neck Surgery, Shifa International Hospital, Islamabad, Pakistan.
  • Mohammad Umair Department of Emergency Medicine, Shifa International Hospital, Islamabad, Pakistan.
  • Abdullah Faisal Dar 1st Year MBBS Student, Shifa International Hospital, Islamabad, Pakistan

DOI:

https://doi.org/10.47391/JPMA.10310

Keywords:

Diagnostic accuracy, Fungal sinusitis, Double density

Abstract

Objective: To compare double-density sign on non-contrast computed tomography scan of paranasal sinuses with fungal sinusitis on histopathology.

Method: The prospective, cross-sectional, randomised study was conducted at the Shifa International Hospital, Islamabad, Pakistan, from July 1, 2021, to June 30, 2023, and comprised patients of either gender aged 20-60 years who were set to undergo functional endoscopic sinus surgery. Demographic characteristics and non-contrast computed tomography scan findings were recorded pre-operatively, while microbiological and histopathology results were recorded post-operatively. The microbiological finding was taken as the gold standard. Data was analysed using SPSS 23.

Results: Of the 201 patients, 123(61.2%) were males and 78(38.8%) were females. The overall mean age was 41.62±8.52 years. The diagnostic accuracy of a double-density sign on computed tomography scan showed sensitivity 90%, specificity 90.8%, positive predictive value 84%, and negative predictive value 94.4%.

Conclusion: A higher rate of sensitivity and specificity indicated that non-contrast computed tomography scan was an effective modality that could be used for the diagnosis of fungal sinusitis.

Key Words: Diagnostic accuracy, Fungal sinusitis, Double density.

Published

2024-06-28

How to Cite

Hadia Wali, Shayan Shahid Ansari, Mohammad Umair, & Abdullah Faisal Dar. (2024). Diagnostic accuracy of double density sign on CT scan of para-nasal sinuses for fungal sinusitis taking microbiology culture as gold standard. Journal of the Pakistan Medical Association, 74(7), 1261–1264. https://doi.org/10.47391/JPMA.10310

Issue

Section

Research Article