The role of 18F-FDG PET/CT in evaluation of Primary CNS lymphoma: The path less travelled

Authors

  • Sharjeel Usmani Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman.
  • Anjali Jain Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman
  • Khulood Al Riyami Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman
  • Shah P Naumani Department of Radiology, Stony Brook University, New York USA
  • Rashid Al-Sukaiti Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCCRC), Muscat Oman
  • Muhammad Shahzad Shamim Aga Khan University Hospital, Karachi, Pakistan.

DOI:

https://doi.org/10.47391/JPMA.23-59

Keywords:

18F-FDG PET/CT

Abstract

Primary central nervous system lymphoma (PCNSL) is a rare but highly aggressive lymphoma with increasing incidence in immunocompromised patients. MRI is the modality of choice in evaluating brain lesions. However, MRI is often challenging in the detection of early recurrence, assessing residual disease and response evaluation in PCNSL. 18F-FDG PET/CT has superior diagnostic performance compared with body CT in the evaluation of lymphoma. 18F-FDG PET-CT is helpful in evaluating evaluation of disease extent and differentiating primary CNS lymphoma from systemic lymphoma. Besides diagnostic and prognostic value in primary CNS lymphoma, it might also be helpful in response assessment. The role of FDG-PET in PCNSL is not fully defined. In this article we have reviewed the potential role of 18F-FDG PET/CT in initial diagnosis, baseline staging, restaging, evaluation of treatment response, prognostication, and survival analysis of PCNSL. Keywords: 18F-FDG PET/CT; CNS lymphoma; brain tumors.

Additional Files

Published

2023-07-15

How to Cite

Sharjeel Usmani, Anjali Jain, Khulood Al Riyami, Shah P Naumani, Rashid Al-Sukaiti, & Muhammad Shahzad Shamim. (2023). The role of 18F-FDG PET/CT in evaluation of Primary CNS lymphoma: The path less travelled. Journal of the Pakistan Medical Association, 73(8), 1744–1746. https://doi.org/10.47391/JPMA.23-59

Issue

Vol. 73 No. 8 (2023): AUGUST

Section

EVIDENCE BASED NEURO-ONCOLOGY

License

Copyright (c) 2023 Journal of the Pakistan Medical Association

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

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