Effect of positive and negative symptoms on schizophrenia related quality of life of hospitalized schizophrenic patients at Sargodha and Lahore: Moderating role of neuropsychiatric symptoms

Abstract

Abstract

Objective: The purpose of study was to find out the moderating effect of neuropsychiatric symptoms in the relationship between positive-negative symptoms of schizophrenia with quality of life of schizophrenic patients.

Subject and Methods: This cross-sectional study was conducted at Lahore and Sargodha, Pakistan. Data was collected by administering the Positive and Negative of Schizophrenia Questionnaire, Quality of Life of Schizophrenia Scale and Neuropsychiatry Inventory.  SPSS-23 has been used for data analysis. The study has been completed in one year. The data was collected from September 4, 2017 to November 1, 2018 after 10am in the morning.

Results: The findings indicate that positive symptoms have significant positive correlation with negative symptoms (p < .001) and neuropsychiatric symptoms (p < .001) whereas significant negative correlation with schizophrenia quality of life (p < .001). Negative symptoms have significant positive correlation with neuropsychiatric symptoms (p < .001) whereas significant negative correlation with schizophrenia related quality of life (p < .001). Neuropsychiatric symptoms have significant negative correlation with schizophrenia quality of life (p < .001) in the study. Moreover, neuropsychiatric symptoms moderated between negative symptoms and schizophrenia related quality of life.

Conclusion: In this study, findings suggested that negative symptoms and neuropsychiatric symptoms have positive association with quality of life of schizophrenic patients whereas positive symptoms have inverse relationship. The study also revealed that neuropsychiatric symptoms enhanced the effect of negative symptoms on quality of life of schizophrenic patients.

Keywords: Schizophrenia, Positive Symptoms, Negative Symptoms, Quality of Life, Neuropsychiatric Symptoms

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