Mammary Analogue Secretory Carcinoma of Parotid gland: literature review and experience of a dedicated cancer institution in Pakistan

Authors

  • Hamza Shahid Department of Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan
  • Rahim Dhanani Department of Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan
  • Muhammad Faisal Department of Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan
  • Abdul Rehman Department of Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan
  • Arif Jamshed Department of Radiation Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan
  • Raza Hussain Department of Surgical Oncology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan

DOI:

https://doi.org/10.47391/JPMA.2371

Abstract

Mammary Analogue Secretory Carcinoma (MASC) is a rare pathology of the salivary gland, most commonly involving the parotid gland. The objective of this study was to identify the characteristic features of MASC and its treatment outcomes. A retrospective review of 12 patients with histological diagnosis of MASC, who were managed between 2010 to 2019, was carried out at the Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore. Their mean age was 34 (±16) years. There were 9 (75%) male and 3 (25%) female patients. Painless slow growing swelling was the most common presenting symptom. All the patients had undergone surgical excision with or without neck dissection, followed by adjuvant treatment. Of these, six patients had T2 tumours, while four had cervical lymph node metastasis. The mean follow-up period was 23 (±21) months. Local recurrence was seen in one patient. MASC is considered a low-grade tumour with good prognosis which can be treated with curative intent of surgery followed by radiotherapy effectively.

Keywords: Mammary analogue secretory carcinoma, Parotid gland, Salivary tumour.

Published

2022-05-10

How to Cite

Hamza Shahid, Rahim Dhanani, Muhammad Faisal, Abdul Rehman, Arif Jamshed, & Raza Hussain. (2022). Mammary Analogue Secretory Carcinoma of Parotid gland: literature review and experience of a dedicated cancer institution in Pakistan. Journal of the Pakistan Medical Association, 72(5), 950–953. https://doi.org/10.47391/JPMA.2371

Issue

Section

Research Article

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