Clinical presentation, diagnostic features on cardiac magnetic resonance imaging and outcome of patients with cardiac amyloidosis presenting to a tertiary care setting

Authors

  • Fateh Ali Tipoo Sultan Department of Medician, Aga Khan University Hospital, Karachi, Pakistan.
  • Muhammad Taha Khan Department of Electrophysiology, National Institute of Cadiovascular Disease, Karachi, Pakistan.

DOI:

https://doi.org/10.47391/JPMA.385

Abstract

Cardiac amyloidosis is a rare disease which is under diagnosed in this region. This study was aimed to assess the clinical presentation, cardiac magnetic resonance  imaging findings and prognosis of patients with cardiac amyloidosis in Pakistani population presenting to a tertiary care setting. A total of eight patients were included with the confirmed diagnosis of cardiac amyloidosis on CMR, after reviewing the CMR data of Aga Khan University Hospital from January 2011 to August 2019. Mean age was 51 + 11.5 years with the majority (75%) being male. All patients presented with heart failure. Sub optimal myocardial nulling on late gadolinium images was the most common finding on CMR. Late gadolinium enhancement was diffuse transmural in 5 patents (62.5%) and diffuse sub-endocardial in 3 patients (37.5%). On a mean follow up of 14 + 10 months, 3 patients (37.5%) died while 7 patients (87.5%) had hospital admissions due heart failure.

Author Biography

Muhammad Taha Khan, Department of Electrophysiology, National Institute of Cadiovascular Disease, Karachi, Pakistan.

achi, Pakistan.

Published

2022-01-05

Issue

Section

Case Series