Prognostic potential of CK-19 managing disseminated oral squamous cell carcinomas in Pakistan: A descriptive cross-sectional study

Authors

  • Waqas Iqbal Department of Oral Pathology, Isra Dental College, Isra University Hyderabad, Pakistan
  • Uzma Tariq Department of Oral Pathology, Isra Dental College, Isra University Hyderabad, Pakistan
  • Arhama Surwaich Department of Oral Pathology, Bhitai Dental and Medical college Mirpurkhas, Pakistan
  • Surwaich Ali channa Department of Oral Pathology, Isra Dental College, Isra University Hyderabad, Pakistan
  • Abdul Majid Department of Pathology, Isra university Hyderabad, Pakistan
  • Shan Ali Department of Microbiology, University of Sindh Jamshoro, Pakistan
  • Naeem Bukhari Centre for Human Genetics, Hazara University Mansehra, Pakistan
  • Admin

DOI:

https://doi.org/10.47391/JPMA.351

Abstract

Abstract

A cross-sectional study was conducted to assess the adoptability of CK-19 as a routine diagnostic assay and potential prognostic marker following disseminated oral squamous cell carcinoma in Pakistani population.

The current descriptive study was conducted at Isra Dental College Hospital, Isra University, Hyderabad, Pakistan. Suspected patients of oral squamous cell carcinomas (OSCC), who visited the Isra Dental College Hospital’s outpatient department from January 2014 up to January 2015 with four year follow up (from January 2015 up to December 2019), were included after ethical approval of the Institutional board. SPSS version 21.0 was used for data analysis.

Sixty cases of oral squamous cell carcinoma (OSCC) were selected for CK-19 quantification by using PCR before and after incisional biopsy.

 

 

Published

2020-11-16

Issue

Section

Case Series