Prevalence of allergic fungal sinusitis among patients with nasal polyposis

Authors

  • Rahim Dhanani Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan
  • Shayan Khalid Ghaloo Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan
  • Basit Salam Department of Radiology, Aga Khan University Hospital, Karachi, Pakistan
  • Hamdan Ahmed Pasha Department of Surgery, Jinnah Medical College Hospital, Karachi, Pakistan
  • Farah Hafiz Yousuf Department of Surgery, Civil Hospital Karachi, Pakistan
  • Mubasher Ikram Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan

DOI:

https://doi.org/10.47391/JPMA.050

Abstract

Abstract

Objective: The objectives of the study were to determine the frequency of AFS among patients with nasal polyps and to compare the Lund-Mackay scores of patients with and without AFS.

Methods: The study was carried out at a tertiary health care center of Karachi, Pakistan from December 2016 to November 2018, after taking ethical approval. Total of 114 patients with sinonasal polyposis undergoing surgery were included. Patients were categorized as case of AFS when histopathology showed allergic mucin with fungal hyphae and culture was positive for fungal growth. Lund-Mackay scoring based on CT PNS of each patient was done and mean scores of AFS and non AFS patients were compared.

Results: Mean age of 114 participants was 37.3 ± 15.3 years. 61 (53.5%) of them were males. 27 (23.7%) patients met the AFS criteria. 19 (16.7%) patients were asthmatic and a significant relationship was found between asthma and AFS (P = 0.03). The mean Lund-Mackay score was 13.2 for non AFS and 18.8 for AFS patients (P = <0.01). Recurrence was seen in 11 (9.6%) cases.

Conclusion: The frequency of AFS in patients with nasal polyps was 23.7% and the patients with AFS showed significantly higher mean Lund-Mackay score compared to non AFS patients.

Continuous....

Published

2021-03-02

How to Cite

Rahim Dhanani, Shayan Khalid Ghaloo, Basit Salam, Hamdan Ahmed Pasha, Farah Hafiz Yousuf, & Mubasher Ikram. (2021). Prevalence of allergic fungal sinusitis among patients with nasal polyposis. Journal of the Pakistan Medical Association, 1-10. https://doi.org/10.47391/JPMA.050

Issue

Section

Research Article