Classification of Non-Insulin Glucose Lowering Drugs


  • Sanjay Kalra Department of Endocrinology, Bharti Hospital, Karnal, India
  • Saurabh Arora Department of Endocrinology, Dayanand Medical College and Hospital, Ludhiana, India
  • Nitin Kapoor Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India; and Non communicable disease unit, The Nossal Institute for Global Health, Melbourne School of Population and global health, University of Melbourne, Victoria, Australia.



The ever-changing scenario of diabetes care, especially pharmacotherapy, calls for a framework to help classify non-insulin glucose drugs. Such a taxonomic structure should be of contemporary relevance as well as futuristic in vision; scholarly
in intent but easy to understand; and based on pathophysiologic principles while being useful for the clinician. We propose a rubric which lists four classes of non-insulin glucose lowering drugs; insulin secretagogues, insulin sensitizers, calorie
restriction mimetics, and calorie restrictors. This classification serves the need of students and teachers as well as pharmacologists and clinicians alike.
Keywords: Alpha glucosidase inhibitors, DPP4i, GLP1RA, liraglutide, pharmacotherapy sulfonylureas, semaglutide, SGLT2i.



How to Cite

Sanjay Kalra, Saurabh Arora, & Nitin Kapoor. (2022). Classification of Non-Insulin Glucose Lowering Drugs. Journal of the Pakistan Medical Association, 72(01).




Most read articles by the same author(s)

1 2 3 4 5 6 7 > >>