Role of surgery in multifocal glioblastoma

Authors

  • Syeda Kubra Kishwar Jafri Section of Neurosurgery, Aga Khan University Hospital, Karachi.
  • Syed Sarmad Bukhari Department of Neurosurgery, Aga Khan University Hospital, Karachi
  • Muhammad Shahzad Shamim Section of Neurosurgery, Department of Surgery, Aga Khan University Hospital, Karachi.

DOI:

https://doi.org/10.47391/JPMA.22-021

Abstract

The management of multifocal glioblastomas is a point of constant discussion amongst neuro-oncologists. Best outcomes in glioblastoma management come from gross total resection (GTR) followed by concomitant radiation and chemotherapy (CCRT). Multifocal disease is resistant to GTR. Conventional management of these lesion is usually biopsy only followed by CCRT. Recent evidence has shown that there may be some benefit to attempting GTR of the largest lesion whenever safe to do so.

Keywords: Glioblastoma multiforme; multifocal; radiotherapy; chemotherapy

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Published

2022-03-03

Issue

Vol. 72 No. 3 (2022): MARCH

Section

EVIDENCE BASED NEURO-ONCOLOGY

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