Meningioma — defining characteristics of the affected Pakistani population

Authors

  • Mashal Murad Shah The Aga Khan University Hospital, Karachi,Pakistan
  • Muhammad Usman Khalid  The Aga Khan University Hospital, Karachi,Pakistan.
  • Mohammad Hamza Bajwa The Aga Khan University Hospital, Karachi,Pakistan.
  • Saqib Kamran Bakhshi The Aga Khan University Hospital, Karachi, Pakistan
  • Saad bin Anis  Shaukat Khanum Cancer Memorial Hospital, Lahore.
  • Naveed Zaman Akhunzada  Rehman Medical Institute, Hayatabad, Peshawar,Pakistan
  • Altaf Ali Laghari  Aga Khan University Hospital, Karachi, Pakistan.
  • Muhammad Faraz Raghib The Aga Khan University Hospital, Karachi,Pakistan
  • Sameen Siddiqi  The Aga Khan University Hospital, Karachi,Pakistan
  • Syed Ather Enam The Aga Khan University Hospital, Karachi,Pakistan

DOI:

https://doi.org/10.47391/JPMA.11-S4-AKUB08

Abstract

Objective: To ascertain the age and gender differences, treatment, and management of meningiomas across Pakistan.

Methods: Data were collected as part of the PBTES, and patients with a histopathological diagnosis of an intracranial meningioma in 2019 that presented at these centres were included in this cohort study sub-analysis. Thirty-two centres participated in the study. Medical students, residents, and faculty collated data from medical records.

Results: Our data indicate that meningiomas constitute 15.6% of all intracranial tumours in Pakistan and occur more often in females (236, 55%) than in males. The mean age at diagnosis was 43.7 ± 19.9 years. Meningiomas had a slightly higher preponderance in the right hemisphere of the brain at 203 (47.32%) tumours and 267 (62.2%) of the tumours in the frontal and parietal lobes. We found that 174 (61.3%) of all meningiomas diagnosed in Pakistan in 2019 were grade I tumours, which was also the most commonly occurring tumour grade. Adjuvant chemoradiotherapy for meningiomas was rarely observed in Pakistan.

Conclusion: The PBTES reveals a low hospital-based incidence of meningiomas in 2019 when compared to the

incidence in high-income countries but found evidence similar to those of other LMICs. Tumour characteristics, such

as location, grading and surgical procedures, were similar to global literature.

Keywords: Meningioma, Chemoradiotherapy, Brain Neoplasms, Epidemiology, Gender traits.

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Published

2022-12-15

How to Cite

Mashal Murad Shah, Muhammad Usman Khalid , Mohammad Hamza Bajwa, Saqib Kamran Bakhshi, Saad bin Anis , Naveed Zaman Akhunzada , Altaf Ali Laghari , Muhammad Faraz Raghib, Sameen Siddiqi , & Syed Ather Enam. (2022). Meningioma — defining characteristics of the affected Pakistani population. Journal of the Pakistan Medical Association, 72(11), S51-S55. https://doi.org/10.47391/JPMA.11-S4-AKUB08

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