Fibrin glue in managing intractable gingival bleeding in patients with inherited bleeding disorders—a quasi-experimental pilot study

Authors

  • Shabneez Hussain Department of Haematology, Indus Hospital and Health Network, Karachi, Pakistan
  • Syed Aijaz Ali Zaidi Department of Oral Medicine, Baqai Dental College, Baqai Medical University, Karachi, Pakistan
  • Sobiya Sawani Department of Community Health Sciences, The Aga Khan University Hospital, Karachi, Pakistan
  • Bushra Moiz Department of Pathology and Microbiology, The Aga Khan University Hospital, Karachi, Pakistan

DOI:

https://doi.org/10.47391/JPMA.9378

Keywords:

Fibrin glue, Inherited blood coagulation disorders, Dental care, blood component transfusion, Oral health

Abstract

This study presents the clinical outcomes of using in-house prepared fibrin glue for controlling gingival bleeding in patients with inherited bleeding disorders (IBD). The objective of the study was to assess the reduction in transfusion days and improvement in compliance for dental evaluation over a one-year period in a low-to-middle-income country. The quasi-experimental pilot study included 40 IBD patients with gingival bleeding. These were divided into two groups: Group A received fibrin glue (n=20), while Group B did not (n=20). The study compared outcome metrics, including the number of treatment days and blood components transfused, using non-parametric tests with a significance threshold of p<0.05. Results showed that Group A required fewer blood components (n=154) as compared to Group B (n=204) (p<0.001).

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Author Biographies

Syed Aijaz Ali Zaidi, Department of Oral Medicine, Baqai Dental College, Baqai Medical University, Karachi, Pakistan

Assistant Professor, Department of Oral Medicine.

Sobiya Sawani, Department of Community Health Sciences, The Aga Khan University Hospital, Karachi, Pakistan

Senior Instructor. Department of Community Health Sciences.

Bushra Moiz, Department of Pathology and Microbiology, The Aga Khan University Hospital, Karachi, Pakistan

Professor, Section of Haematology and Transfusion Medicine.

Published

2024-01-20

How to Cite

Hussain, S., Ali Zaidi, S. A., Sawani, S., & Moiz, B. (2024). Fibrin glue in managing intractable gingival bleeding in patients with inherited bleeding disorders—a quasi-experimental pilot study. Journal of the Pakistan Medical Association, 74(2), 378–383. https://doi.org/10.47391/JPMA.9378

Issue

Section

Short Communication / Short Report

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