Postoperative residual curization in geriatric patients: a prospective, observational cohort study

Authors

DOI:

https://doi.org/10.47391/JPMA.9525

Keywords:

Postoperative residual curarisation, Neuromuscular monitoring, Anaesthesia recovery period, Sugammadex, Postoperative care, Elderly patient

Abstract

Objective: To evaluate the occurrence and potential risk factors of residual curarisation after surgery and the subsequent acute respiratory events in elderly patients.

Method: The prospective, cohort study was conducted at Ankara City Hospital from July to December 2021, and comprised data of geriatric patients undergoing elective surgery under general anaesthesia using moderate-acting nondepolarising muscle relaxants. Postoperative acute respiratory events in the post-anaesthesia care unit were subsequently noted. Data was analysed using SPSS 25.

Results: Of the 185 patients aged >65 years evaluated, 174(94%) were included; 88(50.6%) females and 86(49.4%) males. The incidence of residual curarisation was in 6(3.4%) patients. Postoperative residual curarisation was significantly associated with smooth recovery process (p<0.05). The recovery was associated with intraoperative bleeding, total dose of neuromuscular blocker, and the length of time from the last dose of neuromuscular blocker to antagonist administration (p<0.05). Postoperative critical respiratory events were more common in patients with postoperative residual curarisation (p< 0.001). The length of stay in post-anaesthesia care unit was 1.57 times longer in such patients (p=0.001).

Conclusion: Postoperative residual curarisation increased length of hospital stay and respiratory complications.

Key Words: Postoperative residual curarisation, Neuromuscular monitoring, Anaesthesia recovery period, Sugammadex, Postoperative care, Elderly patient.

Author Biographies

Emine Sonmez, Department of Anaesthesiology and Reanimation, Ankara City Hospital, Ankara, Turkey

Specialist physician

Department of Anesthesiology and Reanimation

Betul Guven Aytac, Department of Anaesthesiology and Reanimation, Ankara City Hospital, Ankara, Turkey

Specialist physician

Department of Anesthesiology and Reanimation

Published

2024-03-20

How to Cite

Sonmez, E., Guven Aytac, B., & Postaci, A. (2024). Postoperative residual curization in geriatric patients: a prospective, observational cohort study. Journal of the Pakistan Medical Association, 74(4), 689–694. https://doi.org/10.47391/JPMA.9525

Issue

Section

Research Article