TY - JOUR AU - Shobha Sapkota , AU - Ammara Kaleem , AU - Suffura Huma , AU - Muhammad Aleem Ud-Din , AU - Shabbir Ahmad , AU - Sobia Shah Alam , PY - 2020/11/20 Y2 - 2024/03/29 TI - Comparison of 3% saline and 0.9% normal saline nebulization as diluent in children with bronchiolitis JF - Journal of the Pakistan Medical Association JA - J Pak Med Assoc VL - 71 IS - 3 SE - Original Article DO - 10.47391/JPMA.569 UR - https://ojs.jpma.org.pk/index.php/public_html/article/view/997 SP - 822-825 AB - <p><strong>Objective:</strong> To compare the outcome in terms of mean time to disappearance of cough, wheezing, crackles and length of hospital stay in patients treated with sodium chloride 3% with sodium chloride 0.9% as nebulisation diluent in children for suffering from bronchiolitis.</p><p><strong>Methods:</strong> The prospective study was conducted at the Department of Paediatric Medicine Sheikh Zayed Hospital, Lahore, Pakistan, from November 2014 to April 2015, and comprised children aged between 6 weeks and 24 months having bronchiolitis. Group A received 3% sodium chloride and Group B received 0.9% of the same solution. Duration of cough, wheezing, crackles and duration of stay at hospital were compared between the groups. Data was analysed using SPSS 17.</p><p><strong>Results:</strong> Of the 100 patients, there were 50(50%) in Group A with a mean age of 7.17±4.46, and as many in Group B with a mean age of 6.6±3.74. Overall, there were 55(55%) boys and 45(45%) girls. Mean cough and wheezing remission time as well as length of hospital stay was significantly different between the groups (p&lt;0.05).</p><p><strong>Conclusion:</strong> In children having bronchiolitis, 3% saline as nebuliser solution was found to be more effective than 0.9% saline solution.</p><p><strong>Key Words:</strong> 3% saline solution, Bronchiolitis, Wheezing, Crepitations, Hospital stay.</p> ER -